Using ARC based grids for NGS read mapping - Grid interface for BWA

Kimmo Mattila

Abstract


This technical note describes a command-line Grid interface for the Burrows-Wheeler Aligner (BWA) read-mapping program. With this interface, BWA jobs can easily utilise Advanced Resource Connector (ARC) middleware-based Grid environments. The interface automatically splits the mapping task into sub-tasks that are executed in parallel in a computing Grid. This approach can significantly speed up the read-mapping process.

Availability: http://www.csc.fi/english/research/sciences/bioscience/programs/BWA


Keywords


read mapping; BWA; grid; ARC

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DOI: https://doi.org/10.14806/ej.18.1.294

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