Automated finished microbial genomes and epigenomes to understand infectious diseases

Ralph Vogelsang

Abstract


Understanding the genetic basis of infectious diseases is critical to enacting effective treatments, and several large-scale sequencing initiatives are underway to collect this information.Therefore, sequencing methods which provide complete, de novo genome assemblies and epigenomes are necessary to fully characterize infectious disease agents in an unbiased, hypothesis-free manner.

Keywords


next generation sequencing; hybrid assembly; non-hybrid assembly

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DOI: https://doi.org/10.14806/ej.19.A.612

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