Taxonomic Assignment in Metagenomics with TANGO

Authors

  • DANIEL ALONSO-ALEMANY Technical University of Catalonia
  • JOSE CARLOS CLEMENTE University of Colorado, Boulder
  • JESPER JANSSON Ochanomizu University
  • GABRIEL VALIENTE Technical University of Catalonia

DOI:

https://doi.org/10.14806/ej.17.2.237

Keywords:

taxonomic assignment, metagenomics

Abstract

One of the main computational challenges facing metagenomic analysis is the taxonomic identification of short DNA fragments. The combination of sequence alignment methods with taxonomic assignment based on consensus can provide an accurate estimate of the microbial diversity in a sample. In this note, we show how recent improvements to these consensus methods, as implemented in the latest release of the TANGO tool, can provide an improved estimate of diversity in simulated data sets.

Embnet.journal 17.2

Downloads

Published

2011-10-10

Issue

Vol. 17 No. 2

Section

Research Papers

License

Authors who publish with this journal agree to the following terms:
  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).