Towards SNP calling in polyploid genomes

Anatoliy Dimitrov, Milko Krachunov, Ognyan Kulev, Jérôme Salse, Irena Avdjieva, Dimitar Vassilev


Polyploid genomes such as hexaploid wheat pose significant study challenges. The detection of SNPs is one of the problems that are difficult to solve. The existence of multiple subgenomes introduces a significant amount of natural noise for the SNP calling algorithms, and the expected occurrence rates of such SNPs is significantly lower than in diploid genomes. This makes them more difficult to distinguish from errors.

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